DNADamage_GN_O6mGN_MMSO4 – DNA base methylation (guanine ==> 6'-O-methylguanine; dimethyl sulfate)
Name | ||
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WID | DNADamage_GN_O6mGN_MMSO4 |
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Name | DNA base methylation (guanine ==> 6'-O-methylguanine; dimethyl sulfate) |
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Classification | ||
Type | base_methylation |
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Reaction | ||
Stoichiometry | [c]: GN + MMSO4 ⇒ MSO4 + O6mGN |
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Energetics | ||
Is spontaneous (pH 7.5, 25C, I = 0) | True |
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Associations | ||
Process | Process_DNADamage |
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Comments | ||
Comments | methylated predominantly in ssDNA by SN2 agents (eg. MMS), 20% of DNA methylation [PUB_0465]; relative rate: 0.25% MMSO4 methylations [PUB_0467] | |
References |
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Metadata | ||
Created | 2012-10-01 15:08:31 | |
Last updated | 2012-10-01 15:16:21 |