DNADamage_GN_O6eGN_DES – DNA base ethylation (guanine ==> 6'-O-ethylguanine; diethyl sulfate)

Name
WID DNADamage_GN_O6eGN_DES View in model
Name DNA base ethylation (guanine ==> 6'-O-ethylguanine; diethyl sulfate) View in model
 
Classification
Type base_ethylation View in model
 
Reaction
Stoichiometry [c]: DES + GN ⇒ ES + O6eGN View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) True View in model
 
Associations
Process Process_DNADamage View in model
 
Comments
Comments relative rate: 0.2% DESethylation [PUB_0467]
References

  1. Beranek DT. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat Res 231, 11-30 (1990). WholeCell: PUB_0467, PubMed: 2195323
 
Metadata
Created 2012-10-01 15:08:31
Last updated 2012-10-01 15:16:21