DHTHY – 5,6-dihydrothymine
Name | ||
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WID | DHTHY |
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Name | 5,6-dihydrothymine |
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Traditional name | 5,6-dihydrothymine | |
IUPAC name | 5-methyl-1,3-diazinane-2,4-dione | |
Cross references | ChEBI: 27468, PubChem: 8144506, KEGG: C00906, BioCyc: DIHYDRO-THYMINE | |
Classification | ||
Type | modified_nucleobase |
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Structure | ||
Empirical formula (pH 7.5) | H8C5N2O2 | |
SMILES (pH 7.5) | CC1CNC(=O)NC1=O | |
Charge (pH 7.5) | 0 | |
Is hydrophobic | False |
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Molecular weight (Da) | 128.13 |
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van der Waals volume (pH 7.5; Å3 molecule‑1) |
112.48 | |
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) | 38.80 | |
logP | -0.670 | |
logD (pH 7.5) | -0.670 | |
Function | ||
Reaction participant | DNA base reduction (thymine ==> 5,6-dihydrothymine; hydrogen radical) [c]: (2) hydrogen_radical + THY ⇒ DHTHY |
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Comments | ||
Comments | recognized by endonuclease III, FPG, UNG [PUB_0473] | |
References |
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Metadata | ||
Created | 2012-10-01 15:06:54 | |
Last updated | 2012-10-01 15:12:03 |