ATPHs_DNASupercoiling_topoisomeraseIV – Negative supercoiling (topoisomerase I)

Name
WID ATPHs_DNASupercoiling_topoisomeraseIV View in model
Name Negative supercoiling (topoisomerase I) View in model
 
Reaction
Stoichiometry [c]: (2) ATP + (2) H2O ⇒ (2) ADP + (2) H + (2) PI View in model
 
Catalysis
Enzyme MG_203_204_TETRAMER [c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
 
Kinetics
Forward kinetics Vmax = 150.0 1/min View in model
 
Associations
Process Process_DNASupercoiling View in model
 
Comments
Comments Reaction occurs with σsp < 0.0 [PUB_0753] with δLK=-2 and kcat=2.5 1/s [PUB_0750].
References

  1. Chen Y, Bjornson K, Redick SD, Erickson HP. A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. Biophys J 88, 505-14 (2005). WholeCell: PUB_0753, PubMed: 15475583

  2. Stone MD, Bryant Z, Crisona NJ, Smith SB, Vologodskii A, Bustamante C, Cozzarelli NR. Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases. Proc Natl Acad Sci U S A 100, 8654-9 (2003). WholeCell: PUB_0750, PubMed: 12857958
 
Metadata
Created 2012-10-01 15:08:06
Last updated 2012-10-01 15:15:00