difloxacin – difloxacin

Name
WID difloxacin View in model
Name difloxacin View in model
Cross references PubChem: 103163868, KEGG: C11234
 
Classification
Type antibiotic_fluoroquinolone View in model
 
Structure
Empirical formula (pH 7.5) H19C21N3O3F2
SMILES (pH 7.5) CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 399.39 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 578.70
 
Comments
Comments Inhibits topoisomerase II/DNA gyrase and topoisomerase IV [PUB_0847].
References
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

 
Metadata
Created 2012-10-01 15:06:54
Last updated 2012-10-01 15:12:03