cyclodA – 8,5'-cyclo-2'-deoxyadenosine

Name
WID cyclodA View in model
Name 8,5'-cyclo-2'-deoxyadenosine View in model
Traditional name 7-amino-15-oxa-2,4,6,9-tetraazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-3(8),4,6,9-tetraene-11,13-diol
IUPAC name 7-amino-15-oxa-2,4,6,9-tetraazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-3(8),4,6,9-tetraene-11,13-diol
Cross references CAS: 117182-88-4, PubChem: 9471068
 
Classification
Type modified_deoxyribonucleoside View in model
 
Structure
Empirical formula (pH 7.5) H11C10N5O3
SMILES (pH 7.5) C1C(C2C(C3=NC4=C(N3C1O2)N=CN=C4N)O)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 249.23 View in model
van der Waals volume 
(pH 7.5; Å3 molecule‑1)
196.44
pI 8.67
logP -1.15
logD (pH 7.5) -1.16
 
Function
Reaction participant View in model
 
Comments
Comments 3 lesions per 10^7 bases [PUB_0479];
References
  1. Guetens G, De Boeck G, Highley M, van Oosterom AT, de Bruijn EA. Oxidative DNA damage: biological significance and methods of analysis. Crit Rev Clin Lab Sci 39, 331-457 (2002). WholeCell: PUB_0479, PubMed: 12385502

 
Metadata
Created 2012-10-01 15:06:53
Last updated 2012-10-01 15:12:00