chloramphenicol – chloramphenicol

Name
WID chloramphenicol View in model
Name chloramphenicol View in model
Cross references PubChem: 46505318, CAS: 56-75-7, KEGG: C00918
 
Classification
Type antibiotic View in model
 
Structure
Empirical formula (pH 7.5) H12C11N2O5Cl2
SMILES (pH 7.5) OCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 323.13 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 167.60
 
Comments
Comments Binds L16 protein of the 50S ribosomal subunit and inhibits amino acid transfer to growing peptide chains [PUB_0847].
References
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

 
Metadata
Created 2012-10-01 15:06:52
Last updated 2012-10-01 15:11:57