azithromycin – azithromycin

Name
WID azithromycin View in model
Name azithromycin View in model
Cross references ChEBI: 2955, PubChem: 46507743, CAS: 83905-01-5, KEGG: C06838
 
Classification
Type antibiotic_macrolide View in model
 
Structure
Empirical formula (pH 7.5) H72C38N2O12
SMILES (pH 7.5) CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 748.98 View in model
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) 1740.90
 
Comments
Comments Binds to the 50S subunit of the 70S bacterial ribosomes, inhibiting RNA-dependent protein synthesis [PUB_0847].
References
  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39, D1035-41 (2011). WholeCell: PUB_0847, PubMed: 21059682

 
Metadata
Created 2012-10-01 15:06:51
Last updated 2012-10-01 15:11:55