ThiL – thiamine-phosphate kinase

Name
WID ThiL View in model
Name thiamine-phosphate kinase View in model
Cross references EC: 2.7.4.16, KEGG: R00617, BiGG: TMPK
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: ATP + THMPADP + TPP View in model
 
Catalysis
Enzyme MG_372_DIMER [c] View in model
Optimal pH
8.0 (dimensionless)
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) 0.0
Keq
1.0 ()
 
Kinetics
Forward kinetics
v = Vmax * [ATP] * [THMP] / (Km1 * Km2 + Km1 * [ATP] + Km2 * [THMP]); Km1 = 1.1 (nM), Km2 = 270 (nM), Vmax = 0.000197 U/mg (Show evidence)
View in model
 
Associations
Pathways COFACTOR_PROSTHETIC_BIOSYNTHESIS
Process Process_Metabolism View in model
 
Comments
References
  1. Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

 
Metadata
Created 2012-10-01 15:09:02
Last updated 2012-10-01 15:17:54