Parameter_0096 – ftsHProteaseSpecificRate

Name
WID Parameter_0096
Name ftsHProteaseSpecificRate
Synonyms FtsH protease specific rate
 
Value
Value
3 (1/s) (Show evidence)
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Associations
Molecules MG_457_HEXAMER
Process Process_ProteinDecay
 
Comments
Comments FstH peptidase kinetic rate. Bruckner et al measured kcat = 22 1/min [PUB_0031]. However combined with the other FtsH parameters, kcat = 3 1/s is needed to keep up with the rate of polypeptide abortion, and in particular to degrade the longest possible aborted polypeptides.
References
  1. Bruckner RC, Gunyuzlu PL, Stein RL. Coupled kinetics of ATP and peptide hydrolysis by Escherichia coli FtsH protease. Biochemistry 42, 10843-52 (2003). WholeCell: PUB_0031, PubMed: 12962509

 
Metadata
Created 2012-10-01 15:09:26
Last updated 2012-10-01 15:18:51