Parameter_0069 – foldChangeSlopes_topoI

Name
WID Parameter_0069
Name foldChangeSlopes_topoI
Synonyms TopoI fold change slopes
 
Value
Value
-7.4 (dimensionless) (Show evidence)
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Associations
Process Process_DNASupercoiling
 
Comments
Comments Topoisomerase I gene expression fold change change per unit superhelical density, sigma. Determined by fitting a piece-wise linear function (linear between foldChangeLowerSigmaLimit=-0.08 and foldChangeUpperSigmaLimit=0.07 and constant outside this region) to experimental fold change versus superhelical density data [PUB_0920].
References
  1. Peter BJ, Arsuaga J, Breier AM, Khodursky AB, Brown PO, Cozzarelli NR. Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli. Genome Biol 5, R87 (2004). WholeCell: PUB_0920, PubMed: 15535863

 
Metadata
Created 2012-10-01 15:09:25
Last updated 2012-10-01 15:18:49