Parameter_0058 – RM_EcoD_RecognitionSequence

Name
WID Parameter_0058
Name RM_EcoD_RecognitionSequence
Synonyms EcoD recognition sequence
 
Value
Value
TTANNNNNNNGTCY (dimensionless) (Show evidence)
View in model
 
Associations
Molecules MG_438_MONOMER
Process Process_DNARepair
 
Comments
Comments EcoDI recognizes the sequence 5'-TTANNNNNNNGTCY-3' [PUB_0542]. The other subunits of the EcoDI restriction/modification system methylate the N6 position of A-3 of hemimethylated DNA producing N6-methyladenine, and cleave unmethylated DNA at a remote site [PUB_0006, PUB_0542, PUB_0543].
References
  1. Keseler IM, Bonavides-Martínez C, Collado-Vides J, Gama-Castro S, Gunsalus RP, Johnson DA, Krummenacker M, Nolan LM, Paley S, Paulsen IT, Peralta-Gil M, Santos-Zavaleta A, Shearer AG, Karp PD. EcoCyc: a comprehensive view of Escherichia coli biology. Nucleic Acids Res 37, D464-70 (2009). WholeCell: PUB_0006, PubMed: 18974181

  2. Loenen WA. Tracking EcoKI and DNA fifty years on: a golden story full of surprises. Nucleic Acids Res 31, 7059-69 (2003). WholeCell: PUB_0543, PubMed: 14654681

  3. Murray NE. Type I restriction systems: sophisticated molecular machines (a legacy of Bertani and Weigle). Microbiol Mol Biol Rev 64, 412-34 (2000). WholeCell: PUB_0542, PubMed: 10839821

 
Metadata
Created 2012-10-01 15:09:24
Last updated 2012-10-01 15:18:48