MG_463_MONOMER – dimethyladenosine transferase

Name
WID	MG_463_MONOMER
Name	dimethyladenosine transferase
Cross references	PDB: 1QYR

Genetics
Gene	MG_463

Structure
Sequence	1 51 101 151 201 251 VNSFFPSRKLGQNFTVNLSVIKRIFAFVKNLNPQAIVEIGVGKGALTNYL LKLKIPYKGIEIDKRLIEYLLVEKILTEDQLVKGDILKKDFNSFFENLSP LLCGNIPYSITSPIINKFLESKLRSFVLMTQKEFANRLLAKVNSSDYSAF GAFCQYYLTITTVFKIDRHAFKPKPKVDSTLILLEKNKSVSYDFKFGLFL KQCFNQRRKMLINNLKHFFAVDYLLNIIQKQNLKTSIRAQELSPCQLFNL YQNICNGKN* 50 100 150 200 250 260
Is N‑terminal methionine cleaved	No
Empirical formula (pH 7.5)	H₂₂₁₄C₁₃₈₆N₃₅₃O₃₆₉S₇
Molecular weight (pH 7.5; Da)	29950.92
Extinction coefficient (260 nm, 25C, pH 7.0)	15525
Instability index	30.73
Is stable	True
Aliphatic index	104.96
GRAVY (25C, pH 7.0)	-0.0415
Half life (OD (600 nm) = 0.3, M9 media, 36C; min)	1200

Synthesis
Localization	c

Function
Enzyme	16S rRNA (adenine-N(6)-)-methyltransferase [c]: AMET + AMP ⇒ AHCYS + H + m6AMP 16S rRNA (adenine-N(6)-)-methyltransferase [c]: AMET + m6AMP ⇒ AHCYS + H + m62AMP 16S rRNA (adenine-N(6)-)-methyltransferase [c]: AMET + AMP ⇒ AHCYS + H + m6AMP 16S rRNA (adenine-N(6)-)-methyltransferase [c]: AMET + m6AMP ⇒ AHCYS + H + m62AMP

Comments
Comments	Functional Macromolecule Functional as monomer [PUB_0324].
References	O'Farrell HC, Scarsdale JN, Rife JP. Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli. J Mol Biol 339, 337-53 (2004). WholeCell: PUB_0324, PubMed: 15136037

Metadata
Created	2012-10-01 15:08:04
Last updated	2012-10-01 15:14:53


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