MG_349 – Replication initiation/membrane attachment protein

Name
WID MG_349 View in model
Name Replication initiation/membrane attachment protein View in model
Symbol dnaB
Protein product MG_349_MONOMER
Cross references GenBank: AAC71574.1, BioCyc: MG_349, CMR: MG_349, SwissProt: P47591
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 444076450291 MG_346 MG_347 MG_348 MG_349 MG_350 MG_351 MG_521 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 446576 (nt), Length: 1215 (nt), Direction: Forward, G/C content: 28.3%, Sequence:
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
851
901
951
1001
1051
1101
1151
1201
ATGGAGGATAGCGTCTTATACTCTTTTTACTTTTGAACGTATATGCAACC
CAACTATTACCGTGTGATCAAAAAAGCAACATCATTTTCTGGATTAGAAA
TGATCTCTCATGCTTATGGTCAAATTGCGGGAGTGGAAGTTGTTGGGTTT
TATTTATGACTAATAACAGAAGCTAATATTCAGGCGTTCAACAGTGAAAT
TAGAACCCCCATTTCACGATTACAAAATGCCTTTAATCCTTTTGAAATTA
AAAAAAACCAAGTCTCTGAATGGATTTATAAAACTATTAGCAAATTAGAG
AGTCTTGGTTTAGTGAGAACTTTTTTTTCACCAAAACGCTCTGAAATAAC
TTTTTGTATTATTGATCCTTTAGATTGGAAAGAATTTAAGCAAAACAAAC
AATTAAAAGAAAAACTAGTTGAGGCAATGGGAAAAGTTGAATATGACCGA
AACTGCTTAGCTTTTGATCAAATCGACAATCTTCAATTTGATAATGCGCT
TGAAATCTCTGCTAACTTTGAAGTTAATTTCACTGCAAACCAAAGCGATG
TTTGATTTAGCTTTAACTTCGAGGAACTACATAAAGAACTTGTAAAAAAC
AAACTTTTAATTTCTTTAGATGAAAAAGCTAAGACTTTAATTAATGGTTA
TTTTGAAAAATACAAGCTTTCATTGCAACAAATTACTGATTGCATCATCA
ACAGTAGTACTCAAGAGAATGAGCTTGATTTTCAAAAGTTAGAAATGATG
TTTTTTCAAATAGTAAAAAATGATACAGCTCCCATTTTAGAAACAGTTTC
AAACAACAAAGACTTTTTTTATAAGAATGAAATTTTAGATGAATCAACAA
AAAAAGCAATAACAGACTGTCATGTAAACTTCAATTCTGAAAAATACCTT
TTTCTTCTATATGGAAAGATAGATGAATCGCAATTGCAATTAGTTAGACA
ATTGAGAAGTGATTATCAACTATTAGATAAAGTAATTAATTTAGTATTAG
ACTTTTCCTTTTGAAAAAATAACGGAATGTGAAGAGAAAAATACATTCTA
AAAATTGCCCAATCCATCAAAATTAATAACAGTCAAAACAGTTATGAAAA
AACCCTTAATAATTTTATTAGAGCACTAACTTTAAATAAAAAGCATTCTT
TAAATAATATAAAACCAGTTGAAAAAACAATTTCCTTTACTGAGTATTTT
GAATTTATTAAATAA
50
100
150
200
250
300
350
400
450
500
550
600
650
700
750
800
850
900
950
1000
1050
1100
1150
1200
1215
View in model
Transcription unit TU_251 View in model
Empirical formula (pH 7.5) H12972C11756N4893O8423P1215
Molecular weight (pH 7.5; Da) 395203.16 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.560583 (dimensionless) (Show evidence)
View in model
Half life
4.425 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
12686300
pI 3.89
 
Comments
Comments forms complex with dnaC, however dnaC not present in M. genitalium and MG_094 has stronger homology to dnaB
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:25
Last updated 2012-10-01 15:13:30