MG_317 – high molecular weight cytadherence accessory protein 3

Name
WID MG_317 View in model
Name high molecular weight cytadherence accessory protein 3 View in model
Symbol hmw3
Synonyms p69
Protein product MG_317_MONOMER
Cross references GenBank: AAC71539.1, CMR: MG_317, BioCyc: MG_317, SwissProt: Q57081
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 393125399925 MG_314 MG_315 MG_316 MG_317 MG_318 MG_319 MG_320 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 395625 (nt), Length: 1800 (nt), Direction: Reverse, G/C content: 34.2%, Sequence:
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
851
901
951
1001
1051
1101
1151
1201
1251
1301
1351
1401
1451
1501
1551
1601
1651
1701
1751
ATGAACGATAAACAGAAAGCTAAAATAAACAAAGCCTATAACAAGCTTTT
AAAAAAGATTAACAAAAGATATCCTGATGTTAGTGTTGTTTATGCCCGTG
ATCATAAAAATAAGGTTCATGCTCTATACCAAGATCCTGAATCAGGTAAT
ATCTTCTCTTTAGAAAAAAGAAAGCAGTTAGCTAGTAACTATCCTTTGTT
TGAATTAACTTCAGATAACCCTATTAGCTTTACAAATAACATTGTTAGCT
TAAATGCTTATGATGATAAGAACAACTTGGTAACTGTTCAATATGATCAG
GATAACAACACTTTCTATGACCAAAATGGTAATGTTTTGGATGTTTCTAG
CTATACTGATGAGAAAAAGGTCCCTTTAATTAACTATTTAAGCAGTACTC
AAACTTCTCAAGAACAACCAACCCAACAAGATTATCCTAGTATTGATGCA
GGTCTTCCTAAGATAGAAGTTGATGACCAACCAAAAGCAGCTCAACACAC
TACTCTAGAAACTGAAAGTGAACCTGATGTCTTTGAATTAAATGACAGTT
TAAATCAACCCCAACAACCTACAGAAAACTTGGGTGATGACCAGTTTGTT
GAAAAAGAAGTGCCACCTACTCAACAGCTCCATCAGGATTTAGTCCACCA
ACAACCCGTTCAAGTTGATAGTGGATCTCAAAACCATAGTTTTAATAATT
CCCCTTCTTTAAAACCACCACTAGTTAATAAACCAGCAAAGTTAGTTCAA
CCTGAAGTAAAACATATTCCTCAAGTTGAAGTTCAACCGAAACCTCAAAT
AGTTGAACCCAAAATTGAACCAAAACCAGAAGTGAAACATGTATCACATG
TTGAAATTCAACCAAAACCAGAAGTGAAACCTGTTGTTGATTCAGTACCA
GAAGTTAAACAACCTGAAGTAAAACATGTACCACATGTTGAAGTTCAACC
AAAACCTGTTGTTGATTTAAAACCTCAAAGGATTGAACCAAGAATTGAAT
CAAAACCAGAAGTAATAAAACATATTCCTCAAGTTGAAGTTCAACCGAAA
GCTCAAATGGTTGAACCAAGAATTGAACCAAAACCTGAAACAAAATACAT
CCCTCAAGTAGAATCAACTCCTCAAGTTGAAGTTCACCACTGAAAACCAG
AAGTAAAAACTGAATATCAACCCCAACAACCATTGCCAACTTCAGGTTTA
CAAATTAAAGTTGTACCAAGATCAGCAGCTTTACTTCAATCAAAATTAGA
CACTGGTTTTCAACCTAGACAAGTTGAACGCACAACTGATTCAGATATCA
CTGTTAGTGTCTCTTCCCACGCTTCTCTTCTAGAGAAAATTAATGCTTTA
AACCACCAAAGGATAATGAGTGATATTGCTCTAAAGAGTGATAACACTAT
AAAAAGTAGCAATTTCAGCCGTTTTTATCCTGAAAATGAGTATGTTGCAA
CTAAATACAGTGATCCACTTTACAGCGATACCAATCAAAGTTTAACTAGT
GATCGTTTTTCTCTTGATTTTGACTACACACCAAAATCTAGAGTCAACAA
TTACACACCATTAAGATCAACTAATTTCCAAAATAATGCTATTTCTAACT
ATCGTTTTAGCAGAACACCAAGTAGTTATTATCCCTTAACAAGAAGACCA
TGAAGATTAACTAATATCAGTTCATACCGTTCATCATTCCATTCACCAAC
AAGACTATCAAGTTTTAGAAGAACTAGTTTACCATTTAGTTCTAGCTATG
ATGGACTTAGACGTTATCCATCAAGATCATATTGATCTAAGGACTTTTAA
50
100
150
200
250
300
350
400
450
500
550
600
650
700
750
800
850
900
950
1000
1050
1100
1150
1200
1250
1300
1350
1400
1450
1500
1550
1600
1650
1700
1750
1800
View in model
Transcription unit TU_217 View in model
Empirical formula (pH 7.5) H19303C17502N7506O12412P1800
Molecular weight (pH 7.5; Da) 589138.45 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
1.29325 (dimensionless) (Show evidence)
View in model
Half life
4.425 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
18489900
pI 3.69
 
Comments
Comments required for property function of adhesins, may help localize adhesins to tip organelle, part of the cytoskeleton-like Triton shell [PUB_0088]; high Pro content, low pI, central acidic Pro-rich domain [PUB_0089];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Proft T, Hilbert H, Plagens H, Herrmann R. The P200 protein of Mycoplasma pneumoniae shows common features with the cytadherence-associated proteins HMW1 and HMW3. Gene 171, 79-82 (1996). WholeCell: PUB_0089, PubMed: 8675035

  4. Razin S, Jacobs E. Mycoplasma adhesion. J Gen Microbiol 138, 407-22 (1992). WholeCell: PUB_0088, PubMed: 1593256

  5. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:24
Last updated 2012-10-01 15:13:26