MG_266 – leucyl-tRNA synthetase

Name
WID MG_266 View in model
Name leucyl-tRNA synthetase View in model
Symbol leuS
Protein product MG_266_MONOMER
Cross references GenBank: AAC71488.1, CMR: MG_266, BioCyc: MG_266, SwissProt: P47508
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 319933327312 MG_263 MG_264 MG_265 MG_266 MG_268 MG_269 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 322433 (nt), Length: 2379 (nt), Direction: Reverse, G/C content: 32.6%, Sequence:
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ATGTACAATCACAATTTAATTGAAGAAAAGTGGTTAAAAAAATGAAAAAA
CAAAGATGTTAACCGCTTTGAAAGCGATAGTAACAAAAAGAAATATTATG
TCCTTGACATGTTCCCTTATCCCTCAGCAGCAGGATTACATTTAGGACAT
GTTAGAGCTTATACTATCACTGATGTAATAAGTAGGTATTACAAAGCTAA
AGGATTTAATGTGATCCATCCGATTGGTTTTGATGCTTTTGGTTTACCTG
CTGAACAGTATGCTATTAACTCTAATCAAAACCCTGGCAGTTGAACAGAT
CAAAACATTAATAACTTTATTAATCAATTAACTAGTTTTGGTTTTGATTA
TGACTATCATTTAAGTCTCAAAACAACTGATCCACGTTATTACAAATACA
CACAATGGATCTTCAGTGAGCTGTTTAAAGCAAACCTAGCGGAATTAGTT
GATATTGATGTTAATTGGTGTGAACAGCTAGGTACTGTATTGGCTAATGA
AGAAGTTTTAATTGATAGTAATGGCAACGCAGTTAGTGAAAGGGGTTCAT
TTTCAGTTGAAAAACGCAAGATGAAACAGTGAGTTTTGAAAATCACTACT
TTTGCTGATGCACTTCTTGAAGGCTTAGATACACTTGATTGACCTGAACC
AATTAAAGAGATGCAACGGAACTGAATTGGTAAAAGTAAAGGTGTTACTA
TTAACTTTCAACTAAAAGATCATAAGGAAGCTATTGCAATTTTTACAACT
AAACCACAAACAATTTTTGGGGTTAGTTTTCTTGCAGTTTCAACCAACCA
TTGGTTAGCAAAAAAGATAGCAGAAACAAATAAAAAAGTAGCTAGTTTTT
TAAAAAAACAACTCCAGAAAACCACAACTTTAAAGCAAAAAGCAACTTTA
TATGATGGGATAGATTTATTAACAAATGCTATTCACCCTCTTACAAATGA
ATTGATCCCTGTCTATGTTGCTAACTATGTAATTGAAGGATATGGAACAG
ATGCTATTATGGGTGTTGGAGCACACAATGAAAATGATAACTTCTTCGCA
CGTAAACAAAAGTTGAAAATTATCAACGTCATTGATAAAAAAGAACGGCT
GCAAAATTCATTTGCATATAACGGATTAACAACTAAAGAAGCACAAGTAG
CTATTACTAATGAGTTAATTTCACAAAATAAAGCGAAATTAACAACTGTA
TATAAACTGCGTGATTGGATCTTCAGTAGACAGCGTTATTGGGGCGAACC
TTTTCCAATTATTTTTGATGAAAATAACACTCCTCATTTGGTAGAACAAC
TCCCTGTTGAATTACCCTTACTTGAGAATTACAAACCAGATGGAAGTGGT
AATTCTCCACTAATGAGAAATCAAGCTTGGGTAAACATAGTCAAAGATAA
CATCCATTACCAAAGGGAAACTAATACCATGCCCCAATGAGCTGGTTCTT
GTTGGTATTATCTGGGTTATTTAATGTTGATTAAAAACCCTAATTTTTGA
CCAATTGATTCAAAAGAAGCGAAGAAATTATTTGATCAATACCTTCCAGT
TGATCTTTATGTTGGGGGTGCGGAACATGCAGTTTTACACCTTTTGTATG
CCCGTTTTTGACACAAATTTTTGTTTGACAAGAAGCTAGTATCAACAAAA
GAACCATTTCAAAAATTAATTAATCAGGGTATGGTGTTAGGTCCTGATGG
TAAAAAGATGTCCAAATCCAAAGGTAATACCATTAACCCCACACCACTTG
TTGATTCACATGGAGCAGATGCTTTAAGGTTGTACTTAATGTTTATGGGC
CCAATTAGTGCTAGTTTAACTTGAAATGATGAAGGGTTAAACGGGATGAG
AAGGTGATTGGATCGAGTTTATAACTTCTTTTTTAATCATGCTGTTGTTA
CTGATCAAGTTAGTCAAGAGACAATCTTTGCTTACAATTTGTTTTTAAAA
AACAGTTATTGTCATCTTGACAAACATGAACTAAATCTGGTGATTAGTGA
AATGATGATCTTTTTAAACTTTCTCTATAAAACCAAAAAAATTAGCTTAA
ATTATGCAAAGGGATTTTTAACAGTACTGTCGTTTTTTGCGCCCTTTCTT
GCTGAAGAATTGAATGAAAAATGTGGACTTGAACCATTTGTTGTTAAACA
AGCGATTTCTTTAGTTGATTATCAACTTTTTGAGACTGCTAAAACTAAGG
TTATTCTTTCAATTAATGGCAAATTTAAAGCAGCTAAAGAATTTACTAAA
GGTAGTTTAGAGATAGATGTTTTAGAATCATTTAAACAGGATAAAGAGAT
AAATGACATTCTCAACCAACCGATTGAGAGGGTAGTTTATGTTCAGGATC
GAATTATTAATGTTCTTTTAAAAAAATAG
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2379
View in model
Transcription unit TU_176 View in model
Empirical formula (pH 7.5) H25416C23036N9633O16559P2379
Molecular weight (pH 7.5; Da) 775842.55 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.851454 (dimensionless) (Show evidence)
View in model
Half life
2.1 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
24637200
pI 3.95
 
Comments
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:21
Last updated 2012-10-01 15:13:18