MG_235_MONOMER – apurinic endonuclease
Name | ||
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WID | MG_235_MONOMER |
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Name | apurinic endonuclease |
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Cross references | PDB: 2NQJ | |
Genetics | ||
Gene | MG_235 |
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Structure | ||
Sequence | 1 51 101 151 201 251 MPKLLGSFISFKAPNYFVQSAQDAIAIDATALMVFLGPPHSAYRVPFNKM QFSLGYELLKTKNINSNGLVVHAPYIINCASKDPLKQQNAISVLTNEIQL CNLAGAHYLVLHPGSAVAQTTNEALDNLVKVLNQVINKTKTTVICLETMA GKGNEIGRDLTELKYVIDRIVDKDRIGVCLDTCHFHDSGIDFSDLTGVFN TITTKLGFEFLKVIHLNESKNNCGSKKDRHANINAGMIGFENLMKFISHP QIKDLPIILETPSTSLNYPTIYREEISQIRSWFKTYQPDAN* 50 100 150 200 250 292 |
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Is N‑terminal methionine cleaved | No |
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Prosthetic groups |
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DNA footprint | Length: 7 (nt), Binding: dsDNA, Region: dsDNA |
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Empirical formula (pH 7.5) | H2301C1455N386O426S12 | |
Molecular weight (pH 7.5; Da) | 32401.86 |
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Extinction coefficient (260 nm, 25C, pH 7.0) |
19660 | |
Instability index | 26.51 | |
Is stable | True | |
Aliphatic index | 96.85 | |
GRAVY (25C, pH 7.0) | -0.0849 | |
Half life (OD (600 nm) = 0.3, M9 media, 36C; min) |
1200 |
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Synthesis | ||
Localization | c |
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Function | ||
Enzyme |
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Reaction participant |
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Comments | ||
Comments | Functional Macromolecule Functional as monomer [PUB_0076]. Coenzymes Interacts with 3 ZN per monomer as prosthetic group [96]. DNA-binding Ape1 footprint is 7 nt [PUB_0718]. | |
References |
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Metadata | ||
Created | 2012-10-01 15:07:54 | |
Last updated | 2012-10-01 15:14:36 |