MG_235 – apurinic endonuclease

Name
WID MG_235 View in model
Name apurinic endonuclease View in model
Symbol nfo
Protein product MG_235_MONOMER
Cross references GenBank: AAC71456.1, CMR: MG_235, BioCyc: MG_235, SwissProt: P47477
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 277299283175 MG_231 MG_234 MG_235 MG_236 MG_237 MG_238 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 279799 (nt), Length: 876 (nt), Direction: Forward, G/C content: 36.2%, Sequence:
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ATGCCTAAGCTACTGGGTAGCTTTATTAGCTTTAAAGCCCCCAATTACTT
TGTTCAAAGTGCTCAGGATGCAATTGCTATTGATGCAACTGCTCTAATGG
TATTTTTAGGTCCACCCCATTCTGCTTACCGTGTTCCTTTTAACAAGATG
CAGTTTAGTTTGGGCTATGAGTTGTTAAAAACAAAGAATATTAATAGTAA
TGGTTTGGTTGTTCATGCTCCATATATCATTAACTGTGCATCAAAAGACC
CACTAAAACAGCAGAATGCTATCAGTGTTTTAACCAATGAGATTCAGCTT
TGTAACTTGGCTGGTGCTCACTATTTAGTTTTGCATCCAGGTTCTGCAGT
AGCCCAAACAACCAACGAAGCATTAGATAACCTGGTTAAAGTACTCAATC
AAGTTATCAATAAAACCAAAACAACAGTTATTTGCCTTGAAACAATGGCT
GGTAAGGGTAATGAGATAGGCAGAGACTTAACTGAGTTGAAATATGTTAT
TGACAGGATCGTTGATAAAGATAGGATCGGGGTTTGTCTTGATACCTGTC
ACTTCCATGATAGTGGGATTGACTTTAGTGATCTAACTGGTGTTTTTAAC
ACCATTACAACTAAACTTGGTTTTGAGTTTCTCAAAGTAATCCATTTAAA
TGAATCTAAAAATAATTGTGGTTCTAAAAAAGATAGGCATGCTAATATCA
ATGCTGGGATGATTGGTTTTGAGAACTTAATGAAGTTCATTAGTCACCCC
CAAATTAAGGATTTACCTATTATCTTAGAAACCCCTTCAACTAGTTTAAA
CTACCCAACTATTTACCGTGAAGAGATTAGTCAAATCCGCAGCTGATTTA
AAACTTACCAACCAGATGCTAACTAG
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876
View in model
Transcription unit TU_152 View in model
Empirical formula (pH 7.5) H9357C8480N3540O6134P876
Molecular weight (pH 7.5; Da) 286138.74 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.560583 (dimensionless) (Show evidence)
View in model
Half life
4.1 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
8900200
pI 4.04
 
Comments
Comments 5' apurinic site endonuclease [PUB_0072]; can repair strand breaks in DNA [PUB_0072]; FPG glycosylase generates AP sites [PUB_0072];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Carvalho FM, Fonseca MM, Batistuzzo De Medeiros S, Scortecci KC, Blaha CA, Agnez-Lima LF. DNA repair in reduced genome: the Mycoplasma model. Gene 360, 111-9 (2005). WholeCell: PUB_0072, PubMed: 16153783

  3. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  4. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:20
Last updated 2012-10-01 15:13:13