MG_231 – ribonucleoside-diphosphate reductase, alpha chain

Name
WID MG_231 View in model
Name ribonucleoside-diphosphate reductase, alpha chain View in model
Symbol nrdE
Protein product MG_231_MONOMER
Cross references GenBank: AAC71452.1, CMR: MG_231, BioCyc: MG_231, SwissProt: P47473
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 274147281313 MG_227 MG_228 MG_229 MG_230 MG_231 MG_235 MG_236 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 276647 (nt), Length: 2166 (nt), Direction: Forward, G/C content: 35.4%, Sequence:
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2151
ATGACATCCAAAGAAAAAATCCCTACTTTTAATACTGAAGAAGATGTTGA
AAGTTACATTTCTTTTAATGCCCAAGCCAAAATCTATGATGATTTTGCAA
TCGATTTACAAGCAGTTGAAAGCTATATTCAAGAGCATGTAAAACCCAAA
ACTAAGGTCTTTCATTCCACCAAAGAACGCCTTGATTTTCTGATTAAGAA
CGATTATTATGATGAGAAGATCATCAACATGTACAGTTTTGAACAGTTTG
AAGAGATCACCCATAAAGCATATTCATACCGCTTTCGTTATGCTAACTTC
ATGGGAGCATTTAAGTTCTATAATGCCTATGCTTTAAAGACATTTGATGG
TAAGTACTACTTGGAAAACTATGAGGATAGGGTGGTGATGAATGTATTGA
TGTTAGCTAATGGTAACTTCAATAAGGCATTAAAACTCTTAAAACAGATT
ATCCTTAACCGTTTTCAACCAGCAACCCCTACCTTTCTTAATGCTGGTAG
AAAGAAACGTGGTGAATTTGTTTCATGTTACCTGTTAAGGATTGAAGATA
ACATGGAATCAATAGGTAGAGCGATAACAACTACACTACAACTATCAAAA
CGTGATGGGGGAGTAGCACTTTTGCTTTCCAACTTACGTGAAGCGGGAGC
GCCCATCAAAAAGATAGAAAACCAATCATCAGGGATTATCCCAATTATGA
AATTGTTAGAGGACTCTTTTTCCTATTCCAACCAACTTGGACAAAGACAA
GGAGCGGGAGCGGTGTATCTCCATTGTCACCATCCTGATGTTATGCAGTT
TTTAGATACTAAAAGGGAAAATGCTGATGAGAAGATCAGAATTAAATCAC
TCTCCTTAGGACTTGTGATTCCAGATATCACCTTCCAATTAGCAAAAAAT
AACGAGATGATGGCACTTTTCAGTCCATATGATATCTATCAGGAGTATGG
TAAGGCTTTATCTGATATCTCAGTAACTGAGATGTATTATGAATTGCTTG
AAAACCAACGCATTAAAAAGACCTTTATTAGTGCTAGAAAGTTCTTTCAA
ACAATTGCTGAACTCCACTTTGAAAGTGGTTATCCCTACATCTTGTTTGA
TGATACAGTTAACAGGAGAAATGCCCACAAAAACAGGATAGTAATGTCTA
ACCTTTGCAGTGAAATTGTCCAACCATCTTTACCTTCTGAATTCTATTCA
GACCTTACTTTTAAAAAGGTAGGTAGTGATATTAGCTGTAACTTGGGGAG
TTTAAATATTGCTAGAGCAATGGAAAGTGGTAGTGAGTTAGCTGAATTGA
TTCAACTAGCAATTGAATCACTGGATTTAGTGTCAAGGATCAGTAGTTTA
GAAACCGCTCCTTCCATTAAAAAAGGTAATTCAGAAAACCATGCGTTGGG
ATTAGGAGCGATGAACTTACATGGATTTTTAGCAACAAATGCTATCTATT
ATGATTCAAAGGAAGCGGTTGATTTTACTAACATCTTTTTTTATACAGTA
GCATACCATGCGTTTAGTGCTTCCAATAAATTAGCATTGGAACTAGGTAA
ATTTAAAGACTTTGAAAATACTAAATTTGCTGATGGTAGTTACTTTGATA
AGTACACTAAGGTAGCTAGTGACTTTTGAACATGTAAAACAGAAAAAGTT
CAAGCCCTTTTTGATAAATACCAAGTAAAAATTCCAACTCAGGAAAATTG
GAAGCAATTGGTAGCAAGTATCCAAAAAGATGGACTTGCAAACTCCCATT
TAATGGCTATTGCCCCAACTGGATCTATCTCATATCTCTCTTCATGTACC
CCTTCACTTCAACCAGTAGTATCTCCTGTTGAAGTGAGAAAAGAAGGGAA
GTTAGGACGGATTTATGTCCCTGCTTATAAGCTTGATAATGATAACTATC
AGTACTTTAAAGATGGTGCTTATGAACTGGGCTTTGAACCTATTATTAAC
ATAGTAGCAGCAGCCCAACAACATGTTGATCAAGCAATCTCTTTAACCTT
GTTTATGACTGATAAAGCTACCACCAGAGATCTCAATAAAGCTTATATTT
ATGCTTTTAAAAAGGGTTGTAGTTCTATCTATTATGTCAGAGTAAGACAA
GATGTTTTAAAAGATAGTGAAGATCACACTATTAAAATCAAGGATTGTGA
GGTTTGTTCTATCTAA
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2150
2166
View in model
Transcription unit TU_151 View in model
Empirical formula (pH 7.5) H23163C20996N8838O15091P2166
Molecular weight (pH 7.5; Da) 707850.06 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
1.96428 (dimensionless) (Show evidence)
View in model
Half life
1.3 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
22251000
pI 3.93
 
Comments
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:20
Last updated 2012-10-01 15:13:13