MG_227 – thymidylate synthase

Name
WID MG_227 View in model
Name thymidylate synthase View in model
Symbol thyA
Protein product MG_227_MONOMER
Cross references GenBank: AAC71448.1, CMR: MG_227, BioCyc: MG_227, SwissProt: P47469
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 271290277154 MG_225 MG_226 MG_227 MG_228 MG_229 MG_230 MG_231 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 273790 (nt), Length: 864 (nt), Direction: Forward, G/C content: 33.1%, Sequence:
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51
101
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851
ATGAAACAGTATTTAGATTTAGCTAGTTATGTTTTAGCAAATGGTAAAAA
AAGAAAAAACCGTACAGATACAGATACTTTAAGTGTCTTTGGTTACCAGA
TGAAATTTGACCTTACTAATAGTTTTCCTTTATTGACAACTAAAAAGGTT
AATTGGAAGGCAATTGTCCATGAATTGTTGTGATTTATTAAGGGTGATAC
CAACATTAAGTACTTAGTTGATAATGGGGTGAACATCTGAAATGAATGAC
CATATGAAAACTTTAAAAAATCACCAAGTTTTCAAAACGAAACACTCCAA
GAATTTATCTTAAAGGTTAAAACTGATAATGAGTTTGCTAAACAATTTGC
TGATTTGGGTCCTGTTTATGGCAAGCAATGACGTAATTTTAATGGTGTTG
ATCAACTCAAAAAAGTCATCCAAGAGATTAAAGAAAATCCCAACTCAAGA
AGGCTAATTGTCTCAAGCTGAAACCCTAGTGAATTGGAAAAAATGGCATT
GGCTCCTTGTCATTCACTCTTTCAGTTCTATGTTGAAGAAGATAAACTAA
GCTTACAGCTTTACCAGCGCAGCGGTGATATCTTTCTTGGTGTCCCATTT
AACATTGCATCTTACGCCTTACTTGTGTATTTAGTTGCTCATGAAACTAA
GTTAAAACCTGGTTATTTTATCCATACACTAGGAGATGCACATATCTATG
AAAACCACATTGAACAAATTAAATTACAACTAACAAGAACAACCCTAGAC
CCCCCTCAAGTGGTTTTGAAAAGTGATAAATCAATCTTTGCTTATAGTTT
TGATGATATTGAGTTAGTTGGTTATAATTACCATCCATTTATCTATGGGA
GGGTTGCAGTTTAA
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864
View in model
Transcription unit TU_150 View in model
Empirical formula (pH 7.5) H9227C8362N3486O6027P864
Molecular weight (pH 7.5; Da) 281750.47 View in model
 
Functional genomics
Is essential
No (Show evidence)
View in model
Relative expression
1.96428 (dimensionless) (Show evidence)
View in model
Half life
2.8 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
8887500
pI 3.99
 
Comments
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:20
Last updated 2012-10-01 15:13:12