MG_204_MONOMER – DNA topoisomerase IV, A subunit

Name
WID MG_204_MONOMER View in model
Name DNA topoisomerase IV, A subunit View in model
Cross references PDB: 1ZVU
 
Genetics
Gene MG_204 View in model
 
Structure
Sequence
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751
MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILY
GMFQMGLKPTTPYKKSARAVGEIMGKYHPHGDSSIYDAIIRMSQSWKNNW
TTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFD
DSEKEPTVLPTLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQ
PNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKFIIQAKYEVNK
NLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRII
IKHKDFLPAEKIMAFLFKHTQLQVNFNLNNTVIANRFPIQIGLLSYLDHF
LKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS
DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISS
EQLIASEKARNKLLKKQFEGYKKQFHQQRRSQICGFINQKKVEESELIEN
KTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIV
TSLGNIINIPVYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQP
ILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVSAFLQQDDKLI
CLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPL
VMICSDGSVINLKQTELVVVSRMATAKKLPVKKAINYCFSDATNTQLINF
QGKNGSKLITTSELNQMSKTAISQTRFNKLN*
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782
 View in model
Is N‑terminal methionine cleaved
No
 View in model
Empirical formula (pH 7.5) H6444C3994N1054O1163S22
Molecular weight (pH 7.5; Da) 88541.44 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)		 47760
Instability index 30.03
Is stable True
Aliphatic index 101.88
GRAVY (25C, pH 7.0) -0.196
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)		 1200 View in model
 
Synthesis
Localization c View in model
Chaperones MG_392_393_21MER View in model
 
Function
Complex subunit topoisomerase IV
[c]: (2) MG_203_MONOMER + (2) MG_204_MONOMER ⇒ MG_203_204_TETRAMER		 View in model
 
Comments
Comments Functional Macromolecule Functional as hetercomplex (see MG_203_204_TETRAMER) [PUB_0006].
References

  1. Keseler IM, Bonavides-Martínez C, Collado-Vides J, Gama-Castro S, Gunsalus RP, Johnson DA, Krummenacker M, Nolan LM, Paley S, Paulsen IT, Peralta-Gil M, Santos-Zavaleta A, Shearer AG, Karp PD. EcoCyc: a comprehensive view of Escherichia coli biology. Nucleic Acids Res 37, D464-70 (2009). WholeCell: PUB_0006, PubMed: 18974181
 
Metadata
Created 2012-10-01 15:07:52
Last updated 2012-10-01 15:14:34