MG_204_MONOMER – DNA topoisomerase IV, A subunit

Name
WID MG_204_MONOMER View in model
Name DNA topoisomerase IV, A subunit View in model
Cross references PDB: 1ZVU
 
Genetics
Gene MG_204 View in model
 
Structure
Sequence
1
51
101
151
201
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301
351
401
451
501
551
601
651
701
751
MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILY
GMFQMGLKPTTPYKKSARAVGEIMGKYHPHGDSSIYDAIIRMSQSWKNNW
TTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFD
DSEKEPTVLPTLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQ
PNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKFIIQAKYEVNK
NLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRII
IKHKDFLPAEKIMAFLFKHTQLQVNFNLNNTVIANRFPIQIGLLSYLDHF
LKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS
DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISS
EQLIASEKARNKLLKKQFEGYKKQFHQQRRSQICGFINQKKVEESELIEN
KTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIV
TSLGNIINIPVYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQP
ILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVSAFLQQDDKLI
CLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPL
VMICSDGSVINLKQTELVVVSRMATAKKLPVKKAINYCFSDATNTQLINF
QGKNGSKLITTSELNQMSKTAISQTRFNKLN*
50
100
150
200
250
300
350
400
450
500
550
600
650
700
750
782
View in model
Is N‑terminal methionine cleaved
No
View in model
Empirical formula (pH 7.5) H6444C3994N1054O1163S22
Molecular weight (pH 7.5; Da) 88541.44 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
47760
Instability index 30.03
Is stable True
Aliphatic index 101.88
GRAVY (25C, pH 7.0) -0.196
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)
1200 View in model
 
Synthesis
Localization c View in model
Chaperones MG_392_393_21MER View in model
 
Function
Complex subunit topoisomerase IV
[c]: (2) MG_203_MONOMER + (2) MG_204_MONOMERMG_203_204_TETRAMER
View in model
 
Comments
Comments Functional Macromolecule Functional as hetercomplex (see MG_203_204_TETRAMER) [PUB_0006].
References
  1. Keseler IM, Bonavides-Martínez C, Collado-Vides J, Gama-Castro S, Gunsalus RP, Johnson DA, Krummenacker M, Nolan LM, Paley S, Paulsen IT, Peralta-Gil M, Santos-Zavaleta A, Shearer AG, Karp PD. EcoCyc: a comprehensive view of Escherichia coli biology. Nucleic Acids Res 37, D464-70 (2009). WholeCell: PUB_0006, PubMed: 18974181

 
Metadata
Created 2012-10-01 15:07:52
Last updated 2012-10-01 15:14:34