MG_179 – metal ion (cobalt) ABC transporter, ATP-binding protein, putative

Name
WID MG_179 View in model
Name metal ion (cobalt) ABC transporter, ATP-binding protein, putative View in model
Symbol cbiO
Protein product MG_179_MONOMER
Cross references GenBank: AAC71398.1, CMR: MG_179, BioCyc: MG_179, SwissProt: P47425
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 202372208197 MG_175 MG_176 MG_177 MG_178 MG_179 MG_180 MG_181 MG_182 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 204872 (nt), Length: 825 (nt), Direction: Forward, G/C content: 35.6%, Sequence:
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51
101
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751
801
ATGCTACCAACTAAACAAGCTGCTTGTAGTTTTATTAATGTTGCTTTTTC
CTATAATGAACTGCCATTAATTAGGGAACTATCTTTTAGTGTTTATGAGG
GGGAATATGTTTGTATTGTTGGTCATAATGGCAGTGGTAAATCAACCATT
TCCAAACTGTTAACAGGGTTATTAAAGCCCCAGGCAGGTGAGATTAAGAT
CTTTGGTAAAACAGTTGATTTTGATAATGTTAGTTACTTGAGAAATAACA
TTGGGATCATCTTTCAAAACCCTGATAACCAGTTTATTGGGATCACTGTT
GAAGATGACATTGCCTTTGGGCTTGAAAACAAGTGTTTTTCAAGACAGAA
GATAAAAGCCATTATTGATGAAGTTACCCTACAAACCCAAACTGATGGGT
TTATTAAACAAGAACCCCATAACCTATCAGGGGGACAAAAACAACGGGTA
GCAATTGCATCTGTTTTAGCACTAAATCCTGCTATTATCATCTTTGATGA
ATCAACTGCGATGTTAGATCCTAAAGCTAAAAAAACGATTAAGCAGTTTA
TGGTTAAACTAGCCAAACAGGGCAAGTGTGTGATCTCAATTACCCATGAT
ATGGAAGAAGTTACTAAAGCTGATAAGGTGTTAGTAATGAATGAGGGCAA
ACTGATCAAACAAGGTAAACCTGTTGAAGTTTTCACTAGTGAACAAGAGT
TACAAAAAATCCGTTTAGACATCCCTTTTTCACTCAGTCTTTCAACCAAG
ATAAGAGGGATCACTAGTACAATTGATTACCAAACCCTGATTAAATCAAT
TGCCAAGCTGTGAAAAAAAAGATAG
50
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825
View in model
Transcription unit TU_109 View in model
Empirical formula (pH 7.5) H8831C8005N3390O5735P825
Molecular weight (pH 7.5; Da) 269839.08 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.851454 (dimensionless) (Show evidence)
View in model
Half life
3.8 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
8477500
pI 3.88
 
Comments
Comments no predicted substrate binding protein in M. genitalium; cobalt/nickel transporter [PUB_0113, PUB_0440]; associated with the cobalamin (vitamin B12) biosynthetic pathways [PUB_0110];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 31, 474-7 (2003). WholeCell: PUB_0110, PubMed: 12520055, URL: http://www.ncbi.nlm.nih.gov/Structure/

  3. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  4. Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y. KEGG for linking genomes to life and the environment. Nucleic Acids Res 36, D480-4 (2008). WholeCell: PUB_0113, PubMed: 18077471, URL: http://www.genome.jp/kegg/

  5. Ren Q, Chen K, Paulsen IT. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Nucleic Acids Res 35, D274-9 (2007). WholeCell: PUB_0440, PubMed: 17135193, URL: http://membranetransport.org/

  6. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:18
Last updated 2012-10-01 15:13:05