MG_177 – DNA-directed RNA polymerase, alpha subunit

Name
WID MG_177 View in model
Name DNA-directed RNA polymerase, alpha subunit View in model
Symbol rpoA
Protein product MG_177_MONOMER
Cross references GenBank: AAC71396.1, CMR: MG_177, BioCyc: MG_177, SwissProt: P47423
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 201015207002 MG_171 MG_172 MG_175 MG_176 MG_177 MG_178 MG_179 MG_180 MG_181 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 203515 (nt), Length: 987 (nt), Direction: Forward, G/C content: 37.8%, Sequence:
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
851
901
951
ATGGAAAAATTTTTAAAGTACGAAATTAAGGTTAACAACAACCAACCAAC
CAACACTAACCCTAACTATGGGATCTTTGAAGTAGCACCGTTAGAATCAG
GATTTGGGATTACCATTGGTAATGCGATGCGCCGAGTGTTACTTAGTTGT
ATCCCAGGCGCTAGTGTGTTTGCCATTGCCATTAGTGGGGTAAAACAAGA
GTTTAGTAATGTGGAGGGTGTGTTGGAAGATGTGACTGAAATGGTGTTAA
ACTTCAAGCAACTAGTGGTGAGAATCTCTGATCTTTTGTTTGAAGATGGG
GAGATGATCGAACCACCCTTAGAAAGGTGACCAGTTTTAAAAGTTACTGC
TGAAAAAAAGGGTGCAGTATATGCAAAGGATCTTGAGTGTCCAGCTGGTT
TTGAAGTGATTAATAAGGACCTTTATCTCTTCTCTTTACAAAAGGACATG
AAACTAACAGTCAGTGTTTATGTTAAACAGGGTAGGGGCTTTACTAGCTT
TCTTGAAAACAGAGAATTGATCAATTCGCTTGGCATTATTGCTACAGATG
CTAACTTTTCCCCGGTTTTACACTGTGGTTATGAAGTTCAAGAGGTGAAA
ACTTCCAAACAAAAGTTAACTGACCATCTCACCTTTAAGATTGCTACTAA
CGGTGCAATTAAAGCAGTGGATGCGTTTGCTATGGCAGCAAAGATCCTAA
TTGAACACTTAAACCCAATTGTAAGTGTCAATGAGTCAATTAAGAATTTA
ACAATTATCCAAGAGAAAGCAGAGGAAAGAAAGGTGAAATCATTTGCCAA
GCAAATTGAAGAACTTGACTTTACTGTTAGAACCTTTAACTGTTTGAAAA
GAAGTGGGATCCACACACTCCAAGAGTTACTATCAAAGTCATTAACTGAC
ATTAGAGAGATTAGAAACCTAGGTAAGAAATCAGAACGGGAGATTATCAA
AAAGGTGCAAGAGTTAGGTTTAAAATTCCGTTCTTAA
50
100
150
200
250
300
350
400
450
500
550
600
650
700
750
800
850
900
950
987
View in model
Transcription unit TU_107 View in model
Empirical formula (pH 7.5) H10578C9590N4095O6856P987
Molecular weight (pH 7.5; Da) 323464.64 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
1.29325 (dimensionless) (Show evidence)
View in model
Half life
10.0 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
10149000
pI 3.85
 
Comments
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:17
Last updated 2012-10-01 15:13:04