MG_109 – serine/threonine protein kinase, putative

Name
WID MG_109 View in model
Name serine/threonine protein kinase, putative View in model
Symbol prkC
Protein product MG_109_MONOMER
Cross references GenBank: AAC71327.1, CMR: MG_109, BioCyc: MG_109, SwissProt: P47355
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 133605139769 MG_105 MG_106 MG_107 MG_108 MG_109 MG_110 MG_111 MG_112 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 136105 (nt), Length: 1164 (nt), Direction: Forward, G/C content: 32.4%, Sequence:
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ATGGAAGCAATCTTAAAGATAGGTGATATTGTTGAAAATAAGTATCAAAT
TGAAAAGCTTTTAAATAGGGGTGGGATGGATTCCTATCTTTTTTTAGCAA
AAAATTTGAACTTAAAAAACTATGGACCAGTTCAAAAAAAACAGTATGGA
CACTTAGTTTTAAAGGTGGTTCAAAAAAATCCTAAGATTAATGAAAATAA
TTGGAAAAAGTTCCTTGATGAAATGGTAACCACAACTAGAGTGCACCATT
CTAACCTAGTGAAAAGTTTTGATGTGGTGAACCCTTTTTTGAAAATAGTT
CGTGGTAATAAAACAATTGCTCTCAATCAGATAGTGATGATTGCAATGGA
GTATGTTGATGGCCCTTCTTTAAGACAATTGCTTAACAGAAAAGGCTACT
TTAGTGTTAGCGAAGTAGTTTATTACTTTACAAAGATAGTAAAAGCCATT
GATTATCTCCACAGTTTCAAGCACCAAATTATCCACCGTGATCTTAAACC
TGAAAACATCTTATTTACTAGTGATTTAACTGATATTAAACTATTAGATT
TTGGCATTGCTTCAACAGTAGTTAAAGTTGCTGAAAAAACCGAAGTTTTA
ACTGATGAAAATTCACTGTTTGGCACAGTTAGTTATATGATTCCTGATGT
TTTGGAAAGCACAGTTAATAAAGCTGGTAAAAAGGTTAGAAAACCACCCA
ATGCCCAGTATGATATCTACTCGTTAGGAATTATTCTATTTGAGATGTTA
GTTGGTAGAGTTCCATTTAACAAGTCAATTAACCCCAACAAGGAAAGAGA
AACAATCCAAAAAGCACGCAATTTTGACTTACCTTTAATGCAAGCAACTA
GAAGTGATATCCCAAATAGCTTAGAAAATATTGCTTTTCGTTGTACTGCT
GTGAAAAGAGAAAACAATAAGTGACTTTACAGTTCCACAAAAGAACTTTT
AGAAGATTTGGCGAATTGAGAAAATGAACAAGCGATGATTAAACCTGCTA
ATGAAAGGGTTTTAGAAGGGCAGGTGGAAATTAGAGAAATGATGCTTGAA
AAGCCCTTAGCTTGGTATTTCAAAACTTGAGCCTTATCAATCTTTACTAT
CGTTTTTATAGGGTTAATTATTGCTGCAATAGTTCTTTTATTAATTTTTA
ATGCCAGATTCTAA
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1164
View in model
Transcription unit TU_068 View in model
Empirical formula (pH 7.5) H12439C11274N4722O8094P1164
Molecular weight (pH 7.5; Da) 379638.18 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.851454 (dimensionless) (Show evidence)
View in model
Half life
4.425 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
12080300
pI 3.94
 
Comments
Comments serine/threonine-specific and tyrosine-specific protein kinases [PUB_0110]; eukaryotic protein kinase family [PUB_0287];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 31, 474-7 (2003). WholeCell: PUB_0110, PubMed: 12520055, URL: http://www.ncbi.nlm.nih.gov/Structure/

  3. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  4. Leonard CJ, Aravind L, Koonin EV. Novel families of putative protein kinases in bacteria and archaea: evolution of the eukaryotic protein kinase superfamily.. Genome Res 8, 1038-47 (1998). WholeCell: PUB_0287, PubMed: 9799791

  5. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:14
Last updated 2012-10-01 15:12:54