MG_086 – prolipoprotein diacylglyceryl transferase

Name
WID MG_086 View in model
Name prolipoprotein diacylglyceryl transferase View in model
Symbol lgt
Synonyms gerF
Protein product MG_086_MONOMER
Cross references GenBank: AAC71304.1, CMR: MG_086, BioCyc: MG_086, SwissProt: P47332
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 110218116367 MG_083 MG_084 MG_085 MG_086 MG_087 MG_088 MG_089 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 112718 (nt), Length: 1149 (nt), Direction: Forward, G/C content: 32.1%, Sequence:
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ATGAATAGACCAAGTTGATCAACTGCATTTAATATTGGTGGTGGATTTCC
CATCCAGTGGTATGGGATCATTGTCTCAATTGGCATTATTTTTGCCATTT
TAATGTTTGTCTTTAAACTGATTTATTGTTACAAATTACAAGACAACAGT
TTTTATTTTTTTATCTTTATTGCTGTTTTAACGATGGTTTTAGGCGCTCG
CCTCTGGTCATTTGTAATTGGTGATTCCAATTTTGCTAACAACAATTTCT
TTGATTTTCGTAACGGTGGATTGGCCATTCAGGGTGGGATTTTGTTAACC
AGTATTGTCGGAGTAATCTATTTCAACTTCTTTTTAAATAGTAAGACCAA
TAAAACCAAAACGATTGCTGAATTACTGAATAATAAGAATGAAATAAAAG
CTGTTTATGTTGAAAGAAATATCTCTGTTCTAGTGATGTTAGATCTGATT
GCTCCTTGTGTTTTAATTGGTCAAGCAATTGGCAGATGGGGTAATTTTTT
CAACCAAGAAGTTTATGGGTTTGCTTTAGCTGGAACAATGAATGATCCCC
AAGCATTGGCTAATACCCAGTGGGGATTTTTAAAGATCTTAATGCCTAAG
GTTTGGGATGGGATGTGGATTGATGGTCAGTTTCGCATTCCGCTCTTTTT
AATTGAGTCATTTTTTAACACTATTTTCTTTGTGTTAATTTACTTTGTAA
TGGATTTTATTAGGGGAGTTAAAAGTGGCACAATTGGTTTTAGTTATTTT
CTTGCTACTGGAATCATTCGTTTAATCTTGGAAAACTTTAGAGACCAAAC
CTTTTATTTTCAAACTTCAATAACCACTAGTATTTTGTTTATTGTCGTTG
GTATTTTAGGAATTTTTTATTGCCAGTTTATCCATGTCAAATTAAGAAAT
TACTTCTGAACTTATTTCTTTCTTTATGCCTTTTATAAAGTAGCTGCTTT
TTTCACTACACTTTTTTTGAATAACAGAAAGCAAATGGCACAACAGAAGT
TTGCTTTTTATGAAAAATCACTTCCCAATAAGAAGCGTTCTTTTTTTGAA
ATGAAGTATTACAATGATGTAACAACACCCAAAATTTATCGTTTAACTGA
TCAGGAAATGAAGTTATTTGATAAATTAGAGGCAGTTACAACCAGCTAG
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1149
View in model
Transcription unit TU_055 View in model
Empirical formula (pH 7.5) H12190C11040N4395O8164P1149
Molecular weight (pH 7.5; Da) 372651.87 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.369079 (dimensionless) (Show evidence)
View in model
Half life
4.425 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
11704400
pI 4.86
 
Comments
Comments Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins [PUB_0096]; prolipoprotein + L-1-phosphatidyl-glycerol diacylglycerol prolipoprotein + sn-glycerol 1-phosphate [PUB_0266];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Sankaran K, Wu HC. Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. J Biol Chem 269, 19701-6 (1994). WholeCell: PUB_0266, PubMed: 8051048

  4. UniProt Consortium. The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res 37, D169-74 (2009). WholeCell: PUB_0096, PubMed: 18836194, URL: http://www.uniprot.org/uniprot/

  5. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:13
Last updated 2012-10-01 15:12:50