MG_083 – peptidyl-tRNA hydrolase

Name
WID MG_083 View in model
Name peptidyl-tRNA hydrolase View in model
Symbol pth
Protein product MG_083_MONOMER
Cross references GenBank: AAC71301.1, BioCyc: MG_083, CMR: MG_083, SwissProt: P47329
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 107855113425 MG_080 MG_081 MG_082 MG_083 MG_084 MG_085 MG_086 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 110355 (nt), Length: 570 (nt), Direction: Forward, G/C content: 33.5%, Sequence:
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551
ATGCCCACCTATAAACTAATTGTTGGTTTAGGTAACTTAGGTAAAAAGTA
TGAGAAAACTCGCCATAATGCTGGTTTTATGGTGTTAGATAGACTAGCTA
GTTTATTCCACTTAAACTTTGATAAAACCAACAAGTTAGGTGATTATCTT
TTTATTAAAGAAAAAGCAGCAATCTTAGCAAAACCTGCTACCTTTATGAA
TAATAGCGGTCTTTTTGTGAAATGGTTACAAGATCACTTTCAAATTCCGC
TTGCAAACATAATGATAGTCCATGATGAAATAGCGTTTGATTTGGGAGTA
ATTAGGCTTAAAATGCAAGGGAGTGCTAACAATCATAATGGCATAAAATC
AGTAATTAGACATTTAGATACTGAACAGTTCAATCGTTTACGCTTTGGGA
TTAAATCACAAAATACGAGTAACATATTGCATGAACAGGTAATGAGTGAA
TTCCAGAATAGTGAACTGACTAAACTGGAAGTTGCGATTACAAAGTCTGT
TGAACTGTTGAAGCGTTATATTGAAGGAGAAGAGTTACAAAGGTTAATGG
AATATTATCATCATGGCTAG
50
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550
570
View in model
Transcription unit TU_053 View in model
Empirical formula (pH 7.5) H6096C5525N2325O3962P570
Molecular weight (pH 7.5; Da) 186113.54 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.851454 (dimensionless) (Show evidence)
View in model
Half life
4.0 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
5921900
pI 3.93
 
Comments
Comments remove the peptide moieties from immature peptide-tRNAs released from ribosome in case of abortive protein synthesis
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  3. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:13
Last updated 2012-10-01 15:12:50