MG_071 – ATPase, P-type (transporting), HAD superfamily, subfamily IC

Name
WID MG_071 View in model
Name ATPase, P-type (transporting), HAD superfamily, subfamily IC View in model
Symbol mgtA
Synonyms pacL
Protein product MG_071_MONOMER
Cross references GenBank: AAC71289.1, CMR: MG_071, BioCyc: MG_071, SwissProt: P47317
Homologs
 
Classification
Type mRNA View in model
 
Structure
Structure 8942497049 MG_069 MG_070 MG_071 MG_072 View in model
Sequence Chromosome: Mgenitalium_Chr_1, Coordinate: 91924 (nt), Length: 2625 (nt), Direction: Forward, G/C content: 33.7%, Sequence:
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
851
901
951
1001
1051
1101
1151
1201
1251
1301
1351
1401
1451
1501
1551
1601
1651
1701
1751
1801
1851
1901
1951
2001
2051
2101
2151
2201
2251
2301
2351
2401
2451
2501
2551
2601
GTGAACAGTTGAACAGGACTTAGTGAACAAGCGGCAATTAAAAGTCGTCA
AGAACATGGTGCTAATTTTCTTCCTGAGAAAAAAGCTACCCCTTTTTGGT
TGTTATTTCTTCAACAATTTAAAAGTTTAGTTGTTATTCTTTTACTGCTA
GCTAGCTTGTTATCGTTTGTAGTTGCTATTGTCAGTGGTTTGAGAAGTAA
CTGAAACTTTAACCATGATCTGATTATTGAATGGGTTCAACCTTTTATTA
TCTTATTAACTGTTTTTGCCAATTCACTAATTGGTTCTATCCAGGAATTT
AAAGCCCAGAAATCTGCTAGTGCTTTAAAGTCCTTGACAAAGTCTTTCAC
AAGGGTTTTTAGGAATGGTGAATTAATTAGCATTAATGTTAGTGAAGTTG
TTGTAGGAGATATTATTTTTGTTGATGCAGGAGATATTATCCCTGCTGAT
GGCAAATTACTACAGGTTAATAACTTACGTTGTTTGGAAAGCTTTTTAAC
TGGTGAATCAACTCCAGTTGATAAGACTATTGATAGCAATGAAAAAGCTA
CTATTCTTGAACAGACAAACTTAGTTTTTTCAGGGGCACAAGTAGTTTAT
GGTAGTGGCGTTTTTCAAGTGGAAGCAGTTGGGATTAAAACCCAAGTTGG
AAAAATTGCTAAAACTGTTGATGATAGTGTAACTAAACTCTCACCCTTAC
AACAAAAACTAGAGAAGATAGGAAAGTGATTTAGTTGGTTTGGGCTTGGT
CTTTTTGCTGTAGTTTTTCTTGTCCAAACTGCTTTATTAGGATTTGATAA
TTTCACTAATAACTGATCAATAGCTTTAATTGGTGCTATTGCGCTTGTTG
TTGCAATTATCCCTGAAGGGCTTGTTACTTTTATTAATGTGATCTTTGCA
TTAAGTGTGCAGAAACTAACTAAGCAAAAAGCCATTATTAAGTATTTATC
AGTAATTGAAACACTTGGATCAGTACAAATTATCTGTACTGATAAAACTG
GTACTTTAACCCAAAACCAGATGAAAGTTGTCGATCACTTCTGTTTTAAT
TCAACAACCCAAACTGATCTAGCAAGAGCATTGTGCTTGTGTAATAATGC
TTCTATTTCCAAAGATGCTAATAAAACAGGTGATCCTACTGAAATTGCTC
TCTTGGAATGAAAAGATCGCAGTCAATTAGATTTAAAAACCTATTACAGG
GTTTATGAAAAAGCCTTTGATTCAATCAGAAAACTTATGACAGTTGTTGT
TCAAAAAGACAACCGCTTCATTGTGATTGTTAAAGGTGCTCCTGATGTGT
TATTACCATTATGTAATAACGTTCAAAATGAAGTAAAGAACATTGAAAAC
TTACTTGATCAAAGTGCTGGTCAAGGCTTGCGTACCTTAGCAGTTGCTTT
AAAGGTTTTATATAAGTTTGATCAAAACGATCAGAAGCAAATTGATGAAC
TTGAAAACAACCTTGAATTCCTTGGGTTTGTTAGTTTACAAGACCCACCA
AGAAAAGAAAGTAAGGAAGCGATTTTAGCGTGCAAGAAAGCTAATATAAC
CCCAATAATGATTACAGGGGATCATCTTAAAACTGCAACTGTAATTGCTA
AAGAGTTAGGCATTTTAACTTTAGATAATCAAGCAGTTTTAGGTAGCGAA
CTAGATGAAAAGAAGATCTTGGATTACAGGGTATTTGCTAGAGTAACTCC
CCAACAAAAATTAGCCATTGTTAGTGCTTGAAAAGAAGCGGGATTTACAG
TTAGTGTTACTGGTGATGGGGTGAATGACGCACCTGCATTAATCAAGAGT
GATGTAGGGTGTTGTATGGGGATTACTGGGGTTGATATTGCAAAAGATGC
TAGTGATCTGATTATTAGTGATGATAATTTCGCTACTATAGTAAATGGTA
TTGAGGAGGGTAGAAAAACTTTTTTAACTTGTAAACGAGTTTTATTAAAC
CTGTTTTTAACTTCAATTGCAGGAACAGTTGTAGTTTTATTAGGACTATT
CATCTTAGGACAAGTTTTTAAAACTAATTTATTACAACAAGGTCATGACT
TTCAGGTGTTTAGTCCTACCCAACTGCTAATTATTAACTTGTTTGTTCAT
GGTTTTCCTGCTGTTGCATTAGCAGTACAACCTGTTAAAGAAAAATTGAT
GGTAGGTAGTTTTTCTACTAAAAATCTGTTTTACAACCGCCAGGGATTTG
ATTTAATCTGACAATCACTATTCTTAAGCTTTTTAACTTTATTGTTCTAT
AGCTTAGGAATTATATATGCAATTAATAACCGTGATTTACAAACTAGCGG
GGATCTAATTAATCGTGCTGGATCAACGTGCGGTTTTTTTATTTTGGGTG
CTAGTGCTGCTTTAAACTCATTAAACCTAATGGTAGATAAACCATTGCTT
ATGACAAACCCTTGGTTTTTTAAGTTAGTTTGAATAGGTTCACTTGCTTC
TATACTGGTATTTTTATTGATCATCTTTATCAACCCTTTAGGGTTAGTGT
TTAATGTCTTGCAAGATTTAACTAATCACCCAGTTTTAATAAGCTATAGT
TTTGGGGGAGTTATTTTGTATATGGGGATGAATGAAGTTGTTAAACTTAT
TAGATTAGGTTATGGCAATATTTAA
50
100
150
200
250
300
350
400
450
500
550
600
650
700
750
800
850
900
950
1000
1050
1100
1150
1200
1250
1300
1350
1400
1450
1500
1550
1600
1650
1700
1750
1800
1850
1900
1950
2000
2050
2100
2150
2200
2250
2300
2350
2400
2450
2500
2550
2600
2625
View in model
Transcription unit TU_045 View in model
Empirical formula (pH 7.5) H27956C25330N10365O18476P2625
Molecular weight (pH 7.5; Da) 854498.47 View in model
 
Functional genomics
Is essential
Yes (Show evidence)
View in model
Relative expression
0.560583 (dimensionless) (Show evidence)
View in model
Half life
18.3 (min) (Show evidence)
View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
26958500
pI 4.31
 
Comments
Comments inorganic cation transport ATPase [PUB_0110, PUB_0439]; possibly transports calcium [PUB_0096, PUB_0211]; Flavobacterium odoratum p-type calcium atpase is homologous to eukaryotic sarcoplasmic reticulum p-type calcium atpase [PUB_0213]; sacroplasmic calcium p-type atpase may be catalytically active as a monomer [PUB_0214];
References
  1. Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A 99, 9697-702 (2002). WholeCell: PUB_0602, PubMed: 12119387

  2. Carafoli E, Brini M. Calcium pumps: structural basis for and mechanism of calcium transmembrane transport. Curr Opin Chem Biol 4, 152-61 (2000). WholeCell: PUB_0214, PubMed: 10742184

  3. Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 31, 474-7 (2003). WholeCell: PUB_0110, PubMed: 12520055, URL: http://www.ncbi.nlm.nih.gov/Structure/

  4. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC. Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A 103, 425-30 (2006). WholeCell: PUB_0193, PubMed: 16407165

  5. Norris V, Grant S, Freestone P, Canvin J, Sheikh FN, Toth I, Trinei M, Modha K, Norman RI. Calcium signalling in bacteria. J Bacteriol 178, 3677-82 (1996). WholeCell: PUB_0213, PubMed: 8682765

  6. ... 4 more

  7. Ren Q, Paulsen IT. Large-scale comparative genomic analyses of cytoplasmic membrane transport systems in prokaryotes. J Mol Microbiol Biotechnol 12, 165-79 (2007). WholeCell: PUB_0211, PubMed: 17587866, URL: http://www.membranetransport.org/

  8. Saier MH Jr, Tran CV, Barabote RD. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Nucleic Acids Res 34, D181-6 (2006). WholeCell: PUB_0439, PubMed: 16381841, URL: http://www.tcdb.org/

  9. UniProt Consortium. The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res 37, D169-74 (2009). WholeCell: PUB_0096, PubMed: 18836194, URL: http://www.uniprot.org/uniprot/

  10. Weiner J 3rd, Zimmerman CU, Göhlmann HW, Herrmann R. Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures. Nucleic Acids Res 31, 6306-20 (2003). WholeCell: PUB_0569, PubMed: 14576319

 
Metadata
Created 2012-10-01 15:07:13
Last updated 2012-10-01 15:12:48