MG_004_MONOMER – DNA gyrase, A subunit

Name
WID MG_004_MONOMER View in model
Name DNA gyrase, A subunit View in model
Cross references PDB: 1ZI0
 
Genetics
Gene MG_004 View in model
 
Structure
Sequence
1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
MAKQQDQVDKIRENLDNSTVKSISLANELERSFMEYAMSVIVARALPDAR
DGLKPVHRRVLYGAYIGGMHHDRPFKKSARIVGDVMSKFHPHGDMAIYDT
MSRMAQDFSLRYLLIDGHGNFGSIDGDRPAAQRYTEARLSKLAAELLKDI
DKDTVDFIANYDGEEKEPTVLPAAFPNLLANGSSGIAVGMSTSIPSHNLS
ELIAGLIMLIDNPQCTFQELLTVIKGPDFPTGANIIYTKGIESYFETGKG
NVVIRSKVEIEQLQTRSALVVTEIPYMVNKTTLIEKIVELVKAEEISGIA
DIRDESSREGIRLVIEVKRDTVPEVLLNQLFKSTRLQVRFPVNMLALVKG
APVLLNMKQALEVYLDHQIDVLVRKTKFVLNKQQERYHILSGLLIAALNI
DEVVAIIKKSANNQEAINTLNTKFKLDEIQAKAVLDMRLRSLSVLEVNKL
QTEQKELKDSIEFCKKVLADQKLQLKIIKEELQKINDQFGDERRSEILYD
ISEEIDDESLIKVENVVITMSTNGYLKRIGVDAYNLQHRGGVGVKGLTTY
VDDSISQLLVCSTHSDLLFFTDKGKVYRIRAHQIPYGFRTNKGIPAVNLI
KIEKDERICSLLSVNNYDDGYFFFCTKNGIVKRTSLNEFINILSNGKRAI
SFDDNDTLYSVIKTHGNDEIFIGSTNGFVVRFHENQLRVLSRTARGVFGI
SLNKGEFVNGLSTSSNGSLLLSVGQNGIGKLTSIDKYRLTKRNAKGVKTL
RVTDRTGPVVTTTTVFGNEDLLMISSAGKIVRTSLQELSEQGKNTSGVKL
IRLKDNERLERVTIFKEELEDKEMQLEDVGSKQITQ*
50
100
150
200
250
300
350
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550
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650
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750
800
837
View in model
Is N‑terminal methionine cleaved
Yes
View in model
Empirical formula (pH 7.5) H6761C4152N1148O1264S22
Molecular weight (pH 7.5; Da) 93691.20 View in model
Extinction coefficient 
(260 nm, 25C, pH 7.0)
33405
Instability index 34.44
Is stable True
Aliphatic index 101.62
GRAVY (25C, pH 7.0) -0.231
Half life (OD (600 nm) = 0.3, 
M9 media, 36C; min)
1200 View in model
 
Synthesis
Localization c View in model
Chaperones MG_305_MONOMER, MG_392_393_21MER View in model
 
Function
Complex subunit DNA gyrase
[c]: (2) MG_003_MONOMER + (2) MG_004_MONOMERDNA_GYRASE
View in model
 
Comments
Comments Functional Macromolecule Functional as heterotetramer ((2) MG_003_MONOMER, (2) MG_004_MONOMER) [PUB_0096]. N-terminal methionine cleavage Shewanella oneidensis MR-1 homolog undergoes N-terminal methionine cleavage [PUB_0280].
References
  1. Gupta N, Tanner S, Jaitly N, Adkins JN, Lipton M, Edwards R, Romine M, Osterman A, Bafna V, Smith RD, Pevzner PA. Whole proteome analysis of post-translational modifications: applications of mass-spectrometry for proteogenomic annotation. Genome Res 17, 1362-77 (2007). WholeCell: PUB_0280, PubMed: 17690205

  2. UniProt Consortium. The Universal Protein Resource (UniProt) 2009. Nucleic Acids Res 37, D169-74 (2009). WholeCell: PUB_0096, PubMed: 18836194, URL: http://www.uniprot.org/uniprot/

 
Metadata
Created 2012-10-01 15:07:43
Last updated 2012-10-01 15:14:20