DU – deoxyuridine

Name
WID DU View in model
Name deoxyuridine View in model
Traditional name uridine, 2'-deoxy-
IUPAC name 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Cross references ChEBI: 16450, PubChem: 3809, CAS: 951-78-0, ThreeDMET: B01281, KNApSAcK: C00019697, ... 4 more
 
Classification
Type modified_deoxyribonucleoside View in model
 
Structure
Empirical formula (pH 7.5) H12C9N2O5
SMILES (pH 7.5) C1C(C(OC1N2C=CC(=O)NC2=O)CO)O
Charge (pH 7.5) 0
Is hydrophobic False View in model
Molecular weight (Da) 228.20 View in model
van der Waals volume 
(pH 7.5; Å3 molecule‑1)
189.19
ΔfG'o (pH 7.5, 25C, I = 0; kJ mol‑1) -32.70
pI 3.43
logP -1.51
logD (pH 7.5) -1.52
 
Function
Reaction participant View in model
 
Comments
Comments recognized by endonuclease III, FPG, UNG [PUB_0473]
References
  1. Hatahet Z, Kow YW, Purmal AA, Cunningham RP, Wallace SS. New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase. J Biol Chem 269, 18814-20 (1994). WholeCell: PUB_0473, PubMed: 8034633

 
Metadata
Created 2012-10-01 15:06:55
Last updated 2012-10-01 15:12:05