CsdA – L-cysteine sulfinic acid desulfurase

Name
WID CsdA View in model
Name L-cysteine sulfinic acid desulfurase View in model
Cross references EC: 2.8.1.7, BiGG: CYSSADS, BioCyc: RXN0-279
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: (2) H + SALAALA + SO2 View in model
 
Catalysis
Enzyme MG_336_DIMER [c] View in model
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
 
Kinetics
Forward kinetics v = Vmax * [SALA] / (Km + [SALA]); Km = 0.0035 (nM), Vmax = 16.0 U/mg View in model
 
Associations
Process Process_Metabolism View in model
 
Comments
Comments pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyze the desulfuration of cysteine to alanine and elemental sulfur. Observed kinetic parameters Km=3.5 mM, Vmax 16 U/mg [PUB_0067].
References
  1. Mihara H, Kurihara T, Yoshimura T, Esaki N. Kinetic and mutational studies of three NifS homologs from Escherichia coli: mechanistic difference between L-cysteine desulfurase and L-selenocysteine lyase reactions. J Biochem 127, 559-67 (2000). WholeCell: PUB_0067, PubMed: 10739946

 
Metadata
Created 2012-10-01 15:08:08
Last updated 2012-10-01 15:15:03