CmkA1 – cytidylate kinase (dCMP)

Name
WID	CmkA1
Name	cytidylate kinase (dCMP)
Cross references	SABIO-RK: 17214, EC: 2.7.4.14, BiGG: CYTK2, KEGG: R01665, BioCyc: RXN-7913

Classification
Type	chemical

Reaction
Stoichiometry	[c]: ATP + DCMP ⇔ ADP + DCDP

Catalysis
Enzyme	MG_330_MONOMER [c]
Optimal pH	7.2 (dimensionless)

Energetics
Is spontaneous (pH 7.5, 25C, I = 0)	False
ΔG (pH 7.5, 25C, I = 0; kJ mol^‑1)	0.0
K_eq	1.0 ()

Kinetics
Forward kinetics	v = V_max * [DCMP] / (K_m1 + [DCMP] + ([DCMP]^2 / K_m2)); K_m1 = 94 (nM), K_m2 = 2800 (nM), V_max = 263.0 U/mg (Show evidence) Value: Rate law: VmaxDCMP/(Km1+DCMP+(DCMP^2/Km2)); Km = 0.094 mM, 2.8 mM, Vmax = 263 umol/(minmg) (None) Measured: Yes Species: Escherichia coli References Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Associations
Pathways	NUCLEOTIDE_SALVAGE_PWY
Process	Process_Metabolism

Comments
References	Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

Metadata
Created	2012-10-01 15:08:07
Last updated	2012-10-01 15:15:02


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