AckA – acetate kinase

Name
WID AckA View in model
Name acetate kinase View in model
Cross references EC: 2.7.2.1, SABIO-RK: 5895, BioCyc: ACETATEKIN-RXN, BiGG: ACKr, KEGG: R00315
 
Classification
Type chemical View in model
 
Reaction
Stoichiometry [c]: ACTP + ADPAC + ATP View in model
 
Catalysis
Enzyme MG_357_DIMER [c] View in model
Optimal pH
7.5 (dimensionless)
Optimal temperature
62.0 (C)
 
Energetics
Is spontaneous (pH 7.5, 25C, I = 0) False View in model
ΔG (pH 7.5, 25C, I = 0; kJ mol‑1) 4.50
Keq
0.000567468287487 ()
 
Kinetics
Forward kinetics
v = Vmax * [ADP] * [ACTP] / (Km1 * Km2 + Km3 * [ACTP] + Km2 * [ADP] + [ADP] * [ACTP]); Km1 = 50 (nM), Km2 = 0.34 (nM), Km3 = 360 (nM), Vmax = 68.0 U/mg (Show evidence)
View in model
Backward kinetics
v = Vmax * [ATP] * [AC] / (Km1 * Km2 + Km3 * [AC] + Km2 * [ATP] + [ATP] * [AC]); Vmax = 70.0 U/mg (Show evidence)
View in model
 
Associations
Pathways PYRUVATE_METABOLISM
Process Process_Metabolism View in model
 
Comments
References
  1. Wittig U, Golebiewski M, Kania R, Krebs O, Mir S, Weidemann A, Anstein S, Saric J, Rojas I. In proceedings of the 3rd International workshop on Data Integration in the Life Sciences 2006. Lecture Notes in Bioinformatics 4075, 94-103 (2006). WholeCell: PUB_0100, URL: http://sabio.villa-bosch.de/

 
Metadata
Created 2012-10-01 15:08:05
Last updated 2012-10-01 15:14:55